“We Live in Time,” in which Andrew Garfield and Florence Pugh play two lovers who face life's trials together, is a certified tearjerker. Between their relationship struggles and Almut's (Florence Pugh) battle with cancer, it would be wise to arrive at the cinema with a box of tissues in hand.

But this is not the first romantic drama to take a heartbreaking turn. After watching “We Live in Time” and falling in love with the characters thanks to the wonderful chemistry between Garfield and Pugh, check out these other romantic films that are guaranteed to bring tears to the eyes of even the most emotionally numb.

We've certainly seen romances before where one of the partners has cancer. But The Irreplaceable You puts a twist on the doomed romance trope by focusing not on how the couple deals with the terminal illness, but on what comes next for the survivor. When Abby (Gugu Mbatha-Raw) learns that she has a fatal cancer, one of her biggest concerns (aside from her deteriorating health, of course) is what will happen to her fiancé Sam (Michiel Huisman). As her illness progresses, she finds a new partner to love after she dies, so that she can die knowing he is not alone. Backed by strong performances from Mbatha-Raw and Huisman, “The Irreplaceable You” is perfect to watch when you've had a few glasses of wine and just really need to cry.

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In “About Time,” Tim Lake (Domhall Gleeson) discovers on his 21st birthday that he has the power to go back in time and change the events of that day. At first, he uses this power for selfish reasons, such as getting multiple chances to seduce Mary (Rachel McAdams). But as he grows up, he begins to see his gift as an opportunity to make each day count, rather than simply trying to manipulate it into the way his life should be. About Time shares with We Live in Time a poignant sentimentality about relationships and the presence of two incredibly likable performers, none more so than Andrew Garfield and Florence Pugh.

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Just try to watch “The Notebook” without sobbing. Like generations of viewers before you, you will fail. Based on the equally weepy Nicholas Sparks novel, “The Notebook” tells the love story of Noah (Ryan Gosling) and Allie (Rachel McAdams) from their teenage years to old age in 1940s South Carolina. What is so sad about it, you may ask? The reason Noah regularly tells their story to Allie at the nursing home is that he hopes that hearing about the love they have shared will bring about that all-too-rare moment of clarity when the fog of dementia lifts and Allie remembers him. From start to finish, The Notebook is one of the most emotional cinematic romances of the 21st century.”

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We've seen in movies what happens when one of the romantic leads falls in love and then falls seriously ill. But what about a broken relationship where a dramatic hospitalization brings two ex-lovers back together? In “The Big Sick,” based on the real-life relationship between Kumail Nanjiani and Emily Gordon, Kumail and Emily (Zoe Kazan) immediately spark and start dating. However, they eventually break up, partly because Kumail is torn between his desire to have a relationship with her and his desire not to make waves with his traditional Pakistani family. When Emily falls into a coma to fight a serious infection, Kumail begins to understand what she means to him. The Big Sick is sweet, but dark enough with a sense of humor to keep it from becoming saccharine.

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Based on John Green's best-selling novel, “It's Not the Stars” fits the mold of the traditional terminal illness in a romantic story and brings it to a YA setting. After thyroid cancer spreads to her lungs, Hazel (Shailene Woodley) joins a support group for teenage cancer patients; the two quirky teenagers realize that while the shadow of Hazel's prognosis weighs heavily on their relationship, they have much in common and get to know each other better They begin to get to know each other better. Moreover, Gus's health was much more precarious than they had imagined. The film follows the path of many romance films that have come before it, but “Not Because of the Stars” packs quite an emotional punch.

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